See the book Turtles all the Way Down for a good account of how all of the vaccine safety data is degenerate and referenced to OTHER vaccines as a “control”.
To prove that a treatment is in the interest of your patient, you need first a placebo controlled (or proven best practice controlled) study to prove effectiveness and safety and THEN, you need to be able to show that the treatment (such as a vaccine) has a NET benefit that outweighs the risk of harm.
Pharmaceutical companies like to cite “relative risks” and they have done this a lot with vaccines. If your risk of severe outcomes from the disease is 0.5% for example and the vaccine reduces that to 0.1% then the “relative risk reduction” is 0.4%/0.5% = 80%.
This is an ABSOLUTE risk reduction of 0.4% ARR
Do you take it? You need to know one more thing... what is your risk of a serious side effect from the vaccine? If it is much greater than the ARR you have NET HARM.
If the risk of harm is much less than the risk reduction, then you might want to get the vaccine... depending on how serious the outcome risk of infection is and your risk tolerance.
Finally, studies done prior to the the widespread outbreaks of infection of COVID have no relevance to present day effectiveness of the vaccines in people with previous exposure.
See the book Turtles all the Way Down for a good account of how all of the vaccine safety data is degenerate and referenced to OTHER vaccines as a “control”.
To prove that a treatment is in the interest of your patient, you need first a placebo controlled (or proven best practice controlled) study to prove effectiveness and safety and THEN, you need to be able to show that the treatment (such as a vaccine) has a NET benefit that outweighs the risk of harm.
Pharmaceutical companies like to cite “relative risks” and they have done this a lot with vaccines. If your risk of severe outcomes from the disease is 0.5% for example and the vaccine reduces that to 0.1% then the “relative risk reduction” is 0.4%/0.5% = 80%.
This is an ABSOLUTE risk reduction of 0.4% ARR
Do you take it? You need to know one more thing... what is your risk of a serious side effect from the vaccine? If it is much greater than the ARR you have NET HARM.
If the risk of harm is much less than the risk reduction, then you might want to get the vaccine... depending on how serious the outcome risk of infection is and your risk tolerance.
Finally, studies done prior to the the widespread outbreaks of infection of COVID have no relevance to present day effectiveness of the vaccines in people with previous exposure.